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Sensitivity Science

3. The History of Nightshades as Poisons

Only a few hundred years ago basic botanical knowledge was widespread. Before modern agriculture you had to know your plants if you were going...
pepper varieties

12. The Chemical Complexity and Relatedness of Other Nightshades

Tobacco is clearly the nightshade with the thickest rap sheet with respect to human health problems. Tobacco smoke is known to contain more than...
the nightshade sensitivity puzzle

1. The Trouble With Nightshades. Maybe.

A Field Guide to the Curious Clues of Nightshade Sensitivity My family has been cooking without potatoes, tomatoes, and peppers for 10 years now. I...

11. The Autoimmune Plot Thickens— Tobacco and Inflammatory Bowel Disease

Autoimmune diseases are poorly understood. The elevator pitch explanation is that your immune system gets confused and overactive, and then attacks your body—a very...

6. Norman Childers and the Anti-Arthritis Diet

During the peak of his professional life Norman Childers was an esteemed professor of horticulture, eighteen years the head of department at Rutgers University....

9. The Lectin Hypothesis

Potatoes and other nightshade vegetables—and actually most vegetables—have yet another complicated class of molecular ingredient: lectins. These are proteins that bind to carbohydrates. Like...

2. Nightshades—Just Side Effects?

Medical science doesn't yet fully recognize or understand nightshade sensitivity. With a little logical thinking, we can skip over this gap and still grasp...

Nightshade Sensitivity, a Nutritionist’s Perspective

Talking with Carolyn Denton, MA, LN After years combing digestive health research and finding almost nothing about nightshade sensitivity, it was a relief to finally...

7. The Complex Cost/Benefit Chemistry of Tomatoes

James Roddick produced much of the nightshade focused research of the 70s and 80s. Over the last 20 years the undisputed leader of nightshade...

4. Glycoalkaloids & Tropane Alkaloids

Early chemical discoveries Unknown to the ancients, some interesting chemistry underlies the mystical properties of nightshades. Glycoalkaloids are complex organic molecules that tend towards high...